The antiSMASH region concept#

Currently, there is no good method available to accurately predict gene cluster borders based purely on the submitted sequence data (with the exception of the CASSIS algorithm, which is able to detect co-regulated genes in fungal genomes). In antiSMASH 5, the display of gene clusters change to reflect the fact that the BGC borders are just offsets defined in the cluster detection rules, the antiSMASH developers renamed the highest level that is displayed to “Region”.

A region in antiSMASH 5 and above (and therefore epsSMASH) corresponds to the gene cluster annotation in antiSMASH 4 and earlier.

For more information about the definition of regions in the antiSMASH framework, visit the antiSMASH documentation page